Detalhe da pesquisa
1.
Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue.
Int J Mol Sci
; 23(9)2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35563647
2.
Phenotype onset in Huntington's disease knock-in mice is correlated with the incomplete splicing of the mutant huntingtin gene.
J Neurosci Res
; 97(12): 1590-1605, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282030
3.
Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.
Neurobiol Dis
; 117: 170-180, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29859873
4.
Suppression of tau propagation using an inhibitor that targets the DK-switch of nSMase2.
Biochem Biophys Res Commun
; 499(4): 751-757, 2018 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604274
5.
A de novo compound targeting α-synuclein improves deficits in models of Parkinson's disease.
Brain
; 139(Pt 12): 3217-3236, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27679481
6.
Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons.
Neurobiol Dis
; 69: 263-75, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24844147
7.
Evidence for behavioral benefits of early dietary supplementation with CoEnzymeQ10 in a slowly progressing mouse model of Huntington's disease.
Mol Cell Neurosci
; 49(2): 149-57, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22044764
8.
A therapeutic small molecule lead enhances γ-oscillations and improves cognition/memory in Alzheimer's disease model mice.
bioRxiv
; 2023 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38106006
9.
Distinct Patterns of Gene Expression Changes in the Colon and Striatum of Young Mice Overexpressing Alpha-Synuclein Support Parkinson's Disease as a Multi-System Process.
J Parkinsons Dis
; 13(7): 1127-1147, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37638450
10.
A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease.
J Neurophysiol
; 107(2): 677-91, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072510
11.
Cognitive deficits in a mouse model of pre-manifest Parkinson's disease.
Eur J Neurosci
; 35(6): 870-82, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22356593
12.
A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions.
Mol Cell Neurosci
; 46(3): 597-606, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21193046
13.
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer's Disease Brain Tissue Reveals Disease-Associated Signatures.
Front Pharmacol
; 12: 766082, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34925024
14.
Pharmacological inhibition of nSMase2 reduces brain exosome release and α-synuclein pathology in a Parkinson's disease model.
Mol Brain
; 14(1): 70, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33875010
15.
Dual Neutral Sphingomyelinase-2/Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease.
ACS Chem Biol
; 15(6): 1671-1684, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32352753
16.
Epidural Spinal Cord Stimulation Improves Motor Function in Rats With Chemically Induced Parkinsonism.
Neurorehabil Neural Repair
; 33(12): 1029-1039, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31684831
17.
Deuterium-reinforced linoleic acid lowers lipid peroxidation and mitigates cognitive impairment in the Q140 knock in mouse model of Huntington's disease.
FEBS J
; 285(16): 3002-3012, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29933522
18.
A small molecule ApoE4-targeted therapeutic candidate that normalizes sirtuin 1 levels and improves cognition in an Alzheimer's disease mouse model.
Sci Rep
; 8(1): 17574, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514854
19.
Human Neural Stem Cell Transplantation Rescues Functional Deficits in R6/2 and Q140 Huntington's Disease Mice.
Stem Cell Reports
; 10(1): 58-72, 2018 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29233555
20.
A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing α-Synuclein.
Neurotherapeutics
; 14(4): 1107-1119, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28585223